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Home > Mouse Models for Drug Discovery: Methods and Protocols > Genetically Engineered Mouse Models in Drug Discovery Research
Mouse Models for Drug Discovery: Methods and Protocols |
Gabriele Proetzel; Michael V. Wiles
Humana Press
Mouse Models for Drug Discovery: Methods and Protocols
Genetically Engineered Mouse Models in Drug Discovery Research
Authors

Rosalba Sacca; Sandra J. Engle; Wenning Qin; Jeffrey L. Stock; John D. McNeish

ARI Id

1664232516831_857647

Access

Not Available Free

Pages

37-54

DOI

10.1007/978-1-60761-058-8_3

Chapter URL

https://rd.springer.com/protocol/10.1007/978-1-60761-058-8_3

Table of Contents of Book
Showing 1 to 20 of 26 entries
Chapters/HeadingsAuthor(s)PagesInfo
Front Matter
i-xii
Improving Toxicity Screening and Drug Development by Using Genetically Defined Strains
Michael F.W. Festing
1-21
The Sophisticated Mouse: Protecting a Precious Reagent
Michael V. Wiles; Rob A. Taft
23-36
Genetically Engineered Mouse Models in Drug Discovery Research
Rosalba Sacca; Sandra J. Engle; Wenning Qin; Jeffrey L. Stock; John D. McNeish
37-54
Engineering the Mouse Genome to Model Human Disease for Drug Discovery
Frank Koentgen; Gabriele Suess; Dieter Naf
55-77
Profiling of Drug Action Using Reporter Mice and Molecular Imaging
Gianpaolo Rando; Andrea Biserni; Paolo Ciana; Adriana Maggi
79-92
Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies
Derry C. Roopenian; Gregory J. Christianson; Thomas J. Sproule
93-104
Development of Novel Major Histocompatibility Complex Class I and Class II-Deficient NOD-SCID IL2R Gamma Chain Knockout Mice for Modeling Human Xenogeneic Graft-Versus-Host Disease
Steve Pino; Michael A. Brehm; Laurence Covassin-Barberis; Marie King; Bruce Gott; Thomas H. Chase et al.
105-117
Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans
David V. Serreze; Marijke Niens; John Kulik; Teresa P. DiLorenzo
119-134
Mouse Models of Type II Diabetes Mellitus in Drug Discovery
Helene Baribault
135-155
Cholesterol Absorption and Metabolism
Philip N. Howles
157-179
Collagen-Induced Arthritis in Mice
Lisette Bevaart; Margriet J. Vervoordeldonk; Paul P. Tak
181-192
Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening
John P. Sundberg; Kathleen A. Silva; Caroline McPhee; Lloyd E. King JR
193-213
Models of Metastasis in Drug Discovery
James E. Talmadge
215-233
Methods for Evaluating Effects of an Irinotecan + 5-Fluorouracil/Leucovorin (IFL) Regimen in an Orthotopic Metastatic Colorectal Cancer Model Utilizing In Vivo Bioluminescence Imaging
David Surguladze; Philipp Steiner; Marie Prewett; James R. Tonra
235-252
CML Mouse Model in Translational Research
Cong Peng; Shaoguang Li
253-266
Mouse Models for Studying Depression-Like States and Antidepressant Drugs
Carisa L. Bergner; Amanda N. Smolinsky; Peter C. Hart; Brett D. Dufour; Rupert J. Egan; Justin L. LaPorte et al.
267-282
Virus-Delivered RNA Interference in Mouse Brain to Study Addiction-Related Behaviors
Amy W. Lasek; Nourredine Azouaou
283-298
Experimental Models of Anxiety for Drug Discovery and Brain Research
Peter C. Hart; Carisa L. Bergner; Amanda N. Smolinsky; Brett D. Dufour; Rupert J. Egan; Justin L. LaPorte et al.
299-321
Mouse Models of Neurodegenerative Diseases: Criteria and General Methodology
Christopher Janus; Hans Welzl
323-345
Chapters/HeadingsAuthor(s)PagesInfo
Showing 1 to 20 of 26 entries
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