Search from the table of contents of 2.5 million books
Advanced Search (Beta)
Home > Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications > The Structure and Mechanism of Drug Transporters
Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications |
Swati Nagar; Upendra A. Argikar; Donald Tweedie
Springer US
Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications
The Structure and Mechanism of Drug Transporters
Authors

Arthur G. Roberts

ARI Id

1665328712504_5947152

Access

Not Available Free

Pages

193-234

DOI

10.1007/978-1-0716-1554-6_8

Chapter URL

https://rd.springer.com/protocol/10.1007/978-1-0716-1554-6_8

Table of Contents of Book
Showing 1 to 20 of 39 entries
Chapters/HeadingsAuthor(s)PagesInfo
Front Matter
i-xxvii
Front Matter
1-1
Fundamentals of Enzyme Kinetics: Michaelis-Menten and Non-Michaelis–Type (Atypical) Enzyme Kinetics
Eleanore Seibert; Timothy S. Tracy
3-27
Reversible Mechanisms of Enzyme Inhibition and Resulting Clinical Significance
Barbara Ring; Steven A. Wrighton; Michael Mohutsky
29-50
Irreversible Enzyme Inhibition Kinetics and Drug–Drug Interactions
Michael Mohutsky; Stephen D. Hall
51-88
Multienzyme Kinetics and Sequential Metabolism
Larry C. Wienkers; Brooke M. Rock
89-112
Consideration of the Unbound Drug Concentration in Enzyme Kinetics
Nigel J. Waters; R. Scott Obach; Li Di
113-145
Numerical Methods for Modeling Enzyme Kinetics
Jaydeep Yadav; Ken Korzekwa; Swati Nagar
147-168
Front Matter
169-169
Crystal Structures of Drug-Metabolizing CYPs
D. Fernando Estrada; Amit Kumar; Christopher S. Campomizzi; Natalie Jay
171-192
The Structure and Mechanism of Drug Transporters
Arthur G. Roberts
193-234
Front Matter
235-235
Enzyme Kinetics of Oxidative Metabolism—Cytochromes P450
Ken Korzekwa
237-256
Enzyme Kinetics, Pharmacokinetics, and Inhibition of Aldehyde Oxidase
Erickson M. Paragas; Kanika Choughule; Jeffrey P. Jones; John T. Barr
257-284
Enzyme Kinetics of PAPS-Sulfotransferase
Margaret O. James
285-300
Enzyme Kinetics of Uridine Diphosphate Glucuronosyltransferases (UGTs)
Jin Zhou; Upendra A. Argikar; John O. Miners
301-338
Principles and Experimental Considerations for In Vitro Transporter Interaction Assays
Sid Bhoopathy; Chris Bode; Vatsala Naageshwaran; Erica Weiskircher-Hildebrandt; Venkata Mukkavilli; Ismael J. Hidalgo
339-365
Front Matter
367-367
Prediction of Drug Clearance from Enzyme and Transporter Kinetics
Priyanka R. Kulkarni; Amir S. Youssef; Aneesh A. Argikar
369-417
Systems Biology Approaches to Enzyme Kinetics
Nnenna A. Finn; Andrew D. Raddatz; Melissa L. Kemp
419-440
Chapters/HeadingsAuthor(s)PagesInfo
Showing 1 to 20 of 39 entries
Similar Books
Similar Chapters
Similar Thesis

Similar News

Similar Articles
Similar Article Headings