Chapter: Complexity of Botulinum Neurotoxins: Challenges for Detection Technology

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Home > Botulinum Neurotoxins > Complexity of Botulinum Neurotoxins: Challenges for Detection Technology

Botulinum Neurotoxins |

Andreas Rummel; Thomas Binz

Springer Berlin Heidelberg

Complexity of Botulinum Neurotoxins: Challenges for Detection Technology

Chapter Info

Authors

Martin B. Dorner; K. Melanie Schulz; Skadi Kull; Brigitte G. Dorner

ARI Id

1674219685299_2312819

Access

Open/Free Access

Pages

219-255

DOI

10.1007/978-3-642-33570-9_11

Chapter URL

https://rd.springer.com/chapter/10.1007/978-3-642-33570-9_11

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Chapters/Headings	Author(s)	Pages	Info
Front Matter		i-viii
Genetic Diversity Within Clostridium botulinum Serotypes, Botulinum Neurotoxin Gene Clusters and Toxin Subtypes	Karen K. Hill; Theresa J. Smith	1-20
Assembly and Function of the Botulinum Neurotoxin Progenitor Complex	Shenyan Gu; Rongsheng Jin	21-44
Uptake of Botulinum Neurotoxin in the Intestine	Yukako Fujinaga; Yo Sugawara; Takuhiro Matsumura	45-59
Double Receptor Anchorage of Botulinum Neurotoxins Accounts for their Exquisite Neurospecificity	Andreas Rummel	61-90
The Elusive Compass of Clostridial Neurotoxins: Deciding When and Where to Go?	Kinga Bercsenyi; Francesco Giribaldi; Giampietro Schiavo	91-113
Synchronized Chaperone Function of Botulinum Neurotoxin Domains Mediates Light Chain Translocation into Neurons	Audrey Fischer	115-137
Clostridial Neurotoxin Light Chains: Devices for SNARE Cleavage Mediated Blockade of Neurotransmission	Thomas Binz	139-157
Synaptic Vesicle Proteins: Targets and Routes for Botulinum Neurotoxins	Gudrun Ahnert-Hilger; Agnieszka Münster-Wandowski; Markus Höltje	159-177
Persistence of Botulinum Neurotoxin Inactivation of Nerve Function	Charles B. Shoemaker; George A. Oyler	179-196
Structure-Based Drug Discovery for Botulinum Neurotoxins	Subramanyam Swaminathan	197-218
Complexity of Botulinum Neurotoxins: Challenges for Detection Technology	Martin B. Dorner; K. Melanie Schulz; Skadi Kull; Brigitte G. Dorner	219-255
Progress in Cell Based Assays for Botulinum Neurotoxin Detection	Sabine Pellett	257-285
Transforming the Domain Structure of Botulinum Neurotoxins into Novel Therapeutics	John Chaddock	287-306
Botulinum Toxin: Application, Safety, and Limitations	Hans Bigalke	307-317
Back Matter		319-321
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